R1530

Name: R1530
SKU: A13111
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A13111

Chk2, KDR, FGFR, Aurora A & Cdk2 抑制剂

1 篇发表文献

R1530 是一种吡唑苯并二氮䓬小分子，具有潜在的抗血管生成和抗肿瘤活性。R1530 也是一种 分裂-血管生成抑制剂（MAI），能够抑制多种参与血管生成的受体酪氨酸激酶，如 血管内皮生长因子受体（VEGFR）-1、-2、-3、血小板衍生生长因子受体（PDGFR）β、类FMS酪氨酸激酶（Flt）-3 和 成纤维细胞生长因子受体（FGFR）-1、-2。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥665.00	现货
10mg	¥1,120.00	现货
25mg	¥2,240.00	现货
50mg	¥3,990.00	现货
100mg	¥5,915.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用R1530发表的1篇文献

Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138

生物活性

Discription

R1530 is a pyrazolobenzodiazepine small molecule with potential antiangiogenesis and antineoplastic activities. R1530 is also a mitosis-angiogenesis inhibitor (MAI) that inhibits multiple receptor tyrosine kinases involved in angiogenesis, such as vascular endothelial growth factor receptor (VEGFR)-1, -2, -3, platelet-derived growth factor receptor (PDGFR) beta? FMS-like tyrosine kinase (Flt)-3, and fibroblast growth factor receptor (FGFR) -1, -2.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13111
分子式	C18H14ClFN4O
分子量	356.78
CAS号	882531-87-5
SMILES	CC1=C2C(=NC3=CC(=C(C=C3C(=N2)C4=CC=CC=C4Cl)F)OC)NN1
其他名称	R-1530, R 1530
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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