R428

Name: R428
SKU: A13741
Price: 175 CNY
Rating: 5 (1 reviews)

目录号: A13741

Axl 抑制剂

1 篇发表文献

R428 是一种选择性的小分子抑制剂，针对 Axl 激酶，在转移性乳腺癌模型中显示出阻断肿瘤扩散和延长生存时间的活性。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥525.00	现货
10mg	¥980.00	现货
25mg	¥1,505.00	现货
50mg	¥1,960.00	现货
100mg	¥3,395.00	现货
200mg	¥4,515.00	现货
500mg	¥6,930.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用R428发表的1篇文献

Ofra Novoplansky, .et al. , J Exp Clin Cancer Res, 2024, Nov 20;43(1):308 PMID: 39567998

生物活性

Discription

R428 is a selective small molecule inhibitor of Axl kinase, which showed activity to blocks tumor spread and prolongs survival in models of metastatic breast cancer.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13741
分子式	C30H34N8
分子量	506.64
CAS号	1037624-75-1
SMILES	C1CCN(C1)[C@H]2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76
其他名称	BGB324, BGB 324, BGB-324, R-428
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 6 mg/mL (11.84 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.74 mL	98.69 mL	197.38 mL
0.5 mM	3.95 mL	19.74 mL	39.48 mL
1 mM	1.97 mL	9.87 mL	19.74 mL
5 mM	0.39 mL	1.97 mL	3.95 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 R428 | R428 供应商 | R428 花费 | R428 生产商 | 订购 R428 | R428 代理商 | 购买 1037624-75-1 | 1037624-75-1 供应商 | 1037624-75-1 花费 | 1037624-75-1 生产商 | 订购 1037624-75-1 | 1037624-75-1 代理商