RA190
目录号: A12287
Proteasome 抑制剂
RA190，一种双苄亚甲基哌啶酮，通过与泛素受体RPN13的半胱氨酸88共价结合，抑制蛋白酶体功能。
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生物活性
| Discription | RA190, a bis-benzylidine piperidon, inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13. |
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产品信息
| 目录号 | A12287 |
|---|---|
| 分子式 | C28H23Cl5N2O2 |
| 分子量 | 596.76 |
| CAS号 | 1617495-03-0 |
| SMILES | O=C1/C(CN(C([C@@H](N)CC2=CC=CC=C2)=O)C/C1=C/C3=CC=C(Cl)C(Cl)=C3)=C\C4=CC=C(Cl)C(Cl)=C4.[H]Cl |
| 其他名称 | RA 190, RA-190 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 88 mg/mL (147.46 mM) | |
| Water | Insoluble | ||
| Ethanol | 18 mg/mL (30.16 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.76 mL | 83.79 mL | 167.57 mL |
| 0.5 mM | 3.35 mL | 16.76 mL | 33.51 mL |
| 1 mM | 1.68 mL | 8.38 mL | 16.76 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.35 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1617495-03-0 | 1617495-03-0 供应商 | 1617495-03-0 花费 | 1617495-03-0 生产商 | 订购 1617495-03-0 | 1617495-03-0 代理商