Rabacfosadine

Name: Rabacfosadine
SKU: A21217
Price: 840 CNY
Rating: 5 (288 reviews)

目录号: A21217

cytotoxic agent

Rabacfosadine（GS-9219），一种新型的核苷酸类似物 PMEG 的前体药物，被设计为一种 细胞毒性药物，优先靶向 淋巴细胞。

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规格	价格	库存
1mg	¥840.00	现货
5mg	¥2,205.00	现货
10mg	¥3,290.00	现货
25mg	¥5,320.00	现货
50mg	¥7,385.00	现货
100mg	¥9,695.00	现货
200mg	¥13,055.00	现货
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Data Sheet

SDS

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生物活性

Discription

Rabacfosadine (GS-9219), a novel prodrug of the nucleotide analogue PMEG, is designed as a cytotoxic agent that preferentially targets lymphoid cells.

Cell Research

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Cell Line	Type	Value	Description	References
CCRF-CEM	IC50	0.48 μM	Antiproliferative activity against human CCRF-CEM after 72 hrs by XTT assay	[PMID: 21664011]
HeLa S3	IC50	2.15 μM	Antiproliferative activity against human HeLaS3 after 72 hrs by XTT assay	[PMID: 21664011]
HL-60	IC50	0.78 μM	Antiproliferative activity against human HL60 after 72 hrs by XTT assay	[PMID: 21664011]

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产品信息

目录号	A21217
分子式	C21H35N8O6P
分子量	526.53
CAS号	859209-74-8
SMILES	CCOC([C@H](C)NP(N[C@@H](C)C(OCC)=O)(COCCN1C=NC2=C(NC3CC3)N=C(N)N=C12)=O)=O
其他名称	GS-9219, GS9219, GS 9219; VDC-1101, VDC1101, VDC 1101
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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