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(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.79 mL | 113.93 mL | 227.87 mL |
| 0.5 mM | 4.56 mL | 22.79 mL | 45.57 mL |
| 1 mM | 2.28 mL | 11.39 mL | 22.79 mL |
| 5 mM | 0.46 mL | 2.28 mL | 4.56 mL |
*The above data is based on the productmolecular weight 438.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21939 |
|---|---|
| 作用机制 | Modulator (调节剂) |
| M. Wt | 438.85 |
| Formula | C24H17ClF2N2O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2092917-63-8 |
| Synonyms | VU6008667, VU-6008667 |
| SMILES | O=C1N2C(N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C(C)=C4)C5=C1C=CC=C5 |
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