Radotinib (IY-5511)

Name: Radotinib (IY-5511)
SKU: A13029

目录号: A13029

Bcr-Abl tyrosine 抑制剂?

Radotinib (IY-5511) Chemical Structure

CAS NO. 926037-48-1

Radotinib是一种新型的选择性Bcl-Abl酪氨酸激酶抑制剂。

库存：现货

规格	价格	数量
10 mg	￥ 840.00
25 mg	￥ 1,470.00
50 mg	￥ 2,240.00

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生物活性

Radotinib是一种新型的选择性Bcl-Abl酪氨酸激酶抑制剂。

靶点信息

BCR-ABL1
34 nM

溶解度 *

In vitro	DMSO	94 mg/mL (177.19 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.85 mL	94.25 mL	188.5 mL
0.5 mM	3.77 mL	18.85 mL	37.7 mL
1 mM	1.89 mL	9.43 mL	18.85 mL
5 mM	0.38 mL	1.89 mL	3.77 mL

*The above data is based on the productmolecular weight 530.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13029
作用机制	Inhibitor (抑制剂)
M. Wt	530.5
Formula	C27H21F3N8O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	926037-48-1
Synonyms	IY-5511
SMILES	CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=NC=CN=C5