RAF mutant-IN-1
目录号: A19011
Raf nhibitor
RAF mutant-IN-1 是一种 RAF 激酶抑制剂,从专利 WO2019107987A1 中提取,对 C-RAF340D/Y341D、B-RAFV600E 和 B-RAFWT 的 IC50 值分别为 21 nM、30 nM 和 392 nM。
Discription | RAF mutant-IN-1 is a RAF kinase inhibitor, extracted from patent WO2019107987A1, with IC50 values of 21 nM, 30 nM and 392 nM for C-RAF340D/Y341D, B-RAFV600E and B-RAFWT, respectively. | ||
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目录号 | A19011 |
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分子式 | C23H18Cl3FN6O2S |
分子量 | 567.85 |
CAS号 | 2340020-82-6 |
SMILES | O=C(C1=CSC2=C(N)N=CN=C21)NC3=C(C)C=CC4=C3C=CN=C4NC5=CC=C(O)C(Cl)=C5F.[H]Cl.[H]Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2