Raltegravir (MK-0518)

Name: Raltegravir (MK-0518)
SKU: A10775
Price: 210 CNY
Rating: 5 (3 reviews)

目录号: A10775

HIV-1 integrase 抑制剂

3 篇发表文献

Raltegravir（MK-0518）针对整合酶，这是一种HIV酶，它将病毒的遗传物质整合到人类染色体中，这是HIV病理发生中的一个关键步骤。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥840.00	现货
50mg	¥1,085.00	现货
100mg	¥1,750.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of Raltegravir (MK-0518)

Raltegravir potassium

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Raltegravir (MK-0518)发表的3篇文献

Joanna Ireland, .et al. , Front Microbiol, 2024, Mar 20:15:1385775 PMID: 38572241

Michal S Barski, .et al. , Nat Commun, 2021, Aug 17;12(1):4996 PMID: 34404793

Lea El Khoury, .et al. , PeerJ Preprints, 2019, 7:e27833v1

生物活性

Discription

Raltegravir (MK-0518) targets integrase, an HIV enzyme that integrates the viral genetic material into human chromosomes, a critical step in the pathogenesis of HIV.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10775
分子式	C20H21FN6O5
分子量	444.4
CAS号	518048-05-0
SMILES	CC1=NN=C(O1)C(=O)NC(C)(C)C2=NC(=C(C(=O)N2C)O)C(=O)NCC3=CC=C(C=C3)F
其他名称	Isentress, MK0518, MK-0518
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	80 mg/mL (180.01 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.5 mL	112.51 mL	225.02 mL
0.5 mM	4.5 mL	22.5 mL	45 mL
1 mM	2.25 mL	11.25 mL	22.5 mL
5 mM	0.45 mL	2.25 mL	4.5 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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