产品详情
Rasagiline mesylate是一种不可逆的单胺氧化酶抑制剂,在早期帕金森氏病中用作单一疗法,在较晚期的病例中用作辅助疗法。对于B型MAO,它对A型的选择性是14倍。
靶点信息
MAO-B | MAO-A | |||
4.43 nM | 412 nM |
In vitro (25°C) | DMSO | 49 mg/mL (183.28 mM) | |
Water | 49 mg/mL (183.28 mM) | ||
Ethanol | 49 mg/mL (183.28 mM) | ||
In vivo | Saline | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 37.41 mL | 187.03 mL | 374.06 mL |
0.5 mM | 7.48 mL | 37.41 mL | 74.81 mL |
1 mM | 3.74 mL | 18.7 mL | 37.41 mL |
5 mM | 0.75 mL | 3.74 mL | 7.48 mL |
*The above data is based on the productmolecular weight 267.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A11722 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 267.34 |
Formula | C12H13N.CH4O3S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 161735-79-1 |
SMILES | CS(=O)(=O)O.C#CCN[C@@H]1CCC2=CC=CC=C12 |
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