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Protein Tyrosine Kinases
Protein Tyrosine Kinases - ErbB4/HER4
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EGFR, HER2 and HER4 inhibitor
Epertinib hydrochloride 是一种强效的、口服活性的、可逆的、选择性的酪氨酸激酶抑制剂,针对 EGFR、HER2 和 HER4,其半抑制浓度(IC50s)分别为 1.48 nM、7.15 nM 和 2.49 nM。Epertinib 显示出强大的抗肿瘤活性。
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作用机制
Inhibitor
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作用靶点
ErbB4/HER4
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