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Regorafenib Hydrochloride

Regorafenib Hydrochloride

Name: Regorafenib Hydrochloride
SKU: A11546

目录号: A11546

VEGFR1/2/3/PDGFRβ/Kit/RET/Raf-1 inhibitor

Regorafenib Hydrochloride Chemical Structure

CAS NO. 835621-07-3

Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

库存：现货

规格	价格	数量
50 mg	￥ 756.00
100 mg	￥ 1,302.00
500 mg	￥ 3,864.00

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产品仅用于科学研究，不针对患者销售，望谅解.

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生物活性

Regorafenib Hydrochloride is a multi-target inhibitor for VEGFR1/2/3, PDGFRβ, Kit, RET and Raf-1 with IC50s of 13/4.2/46, 22, 7, 1.5 and 2.5 nM, respectively.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.26 mL	96.29 mL	192.57 mL
0.5 mM	3.85 mL	19.26 mL	38.51 mL
1 mM	1.93 mL	9.63 mL	19.26 mL
5 mM	0.39 mL	1.93 mL	3.85 mL

*The above data is based on the productmolecular weight 519.28. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A11546
作用机制	Inhibitor (抑制剂)
M. Wt	519.28
Formula	C21H16Cl2F4N4O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	835621-07-3
Synonyms	BAY73-4506 hydrochloride
SMILES	ClC1=C(C(F)(F)F)C=C(NC(NC2=C(F)C=C(OC3=CC=NC(C(NC)=O)=C3)C=C2)=O)C=C1.Cl