Repotrectinib

Name: Repotrectinib
SKU: A19850
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A19850

ROS1/TRK 抑制剂

Repotrectinib (TPX-0005) 是一种强效的 ROS1 (IC50=0.07 nM)、TRK (0.83/0.05/0.1 nM=TRKA/B/C) 抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥385.00	现货
5mg	¥630.00	现货
10mg	¥1,155.00	现货
25mg	¥2,135.00	现货
50mg	¥3,430.00	现货
100mg	¥5,040.00	现货
*10mM 1mL in DMSO**	¥665.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

Repotrectinib (TPX-0005) is a potent ROS1 (IC50=0.07 nM), TRK (0.83/0.05/0.1 nM=TRKA/B/C) inhibitor.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19850
分子式	C18H18FN5O2
分子量	355.37
CAS号	1802220-02-5
SMILES	O=C1NC[C@H](C)OC2=CC=C(F)C=C2[C@@H](C)NC3=NC4=C1C=NN4C=C3
其他名称	TPX-0005, TPX0005, TP -0005
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	63 mg/mL (177.27 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (25.32 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	28.14 mL	140.7 mL	281.4 mL
0.5 mM	5.63 mL	28.14 mL	56.28 mL
1 mM	2.81 mL	14.07 mL	28.14 mL
5 mM	0.56 mL	2.81 mL	5.63 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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