Retatrutide
目录号: A22380
Glucagon receptor 激动剂
Retatrutide(LY3437943)是一种三重激动剂肽,针对葡萄糖受体(GCGR)、依赖葡萄糖的胰岛素促进多肽受体(GIPR)和类葡萄糖肽-1受体(GLP-1R)。Retatrutide与人类的GCGR、GIPR和GLP-1R结合,其EC50值分别为5.79、0.0643和0.775 nM。Retatrutide可用于肥胖症的研究。
Glucagon receptor 激动剂
Discription | Retatrutide (LY3437943) is a triple agonist peptide of the glucagon receptor (GCGR), glucosedependent insulinotropic polypeptide receptor (GIPR), and glucagon-like peptide-1 receptor (GLP-1R). Retatrutide binds human GCGR, GIPR, and GLP-1R with EC50 values of 5.79, 0.0643 and 0.775 nM, respectively. Retatrutide can be used for the research of obesity. |
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目录号 | A22380 |
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分子式 | C221H342N46O68 |
分子量 | 4731.33 |
CAS号 | 2381089-83-2 |
Sequence | Tyr-{Aib}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{α-Me-Leu}-Leu-Asp-Lys-{diacid-C20-gamma-Glu-(AEEA)-Lys}-Ala-Gln-{Aib}-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
其他名称 | LY3437943 |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2