Reversine

Name: Reversine
SKU: A13250
Price: 175 CNY
Rating: 5 (2 reviews)

目录号: A13250

human A3 adenosine receptor 拮抗剂 /Aurora 抑制剂

2 篇发表文献

Reversine 是一种强效的人类 A3 腺苷受体拮抗剂，其 Ki 值为 0.66 μM，同时也是一种全泛 Aurora A/B/C 激酶抑制剂，其 IC50 分别为 12 nM、13 nM 和 20 nM。此外，Reversine 还用于干细胞去分化。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
2mg	¥280.00	现货
5mg	¥385.00	现货
10mg	¥525.00	现货
25mg	¥1,120.00	现货
50mg	¥1,610.00	现货
100mg	¥2,835.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Reversine发表的2篇文献

Amy H. Ide, .et al. , Mol Biol Cell, 2023, Jun 1;34(7):ar76 PMID: 37126397

Hazheen K, .et al. , J Biol Chem, 2020, August 20

生物活性

Discription

Reversine is a potent human A3 adenosine receptor antagonist with Ki of 0.66 μM, and a pan-aurora A/B/C kinase inhibitor with IC50 of 12 nM/13 nM/20 nM, respectively. Also used for stem cell dedifferentiation.

Targets

Target	Value

产品信息

目录号	A13250
分子式	C21H27N7O
分子量	393.5
CAS号	656820-32-5
SMILES	C1CCC(CC1)NC2=NC(=NC3=C2NC=N3)NC4=CC=C(C=C4)N5CCOCC5
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 4 mg/mL (10.17 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.41 mL	127.06 mL	254.13 mL
0.5 mM	5.08 mL	25.41 mL	50.83 mL
1 mM	2.54 mL	12.71 mL	25.41 mL
5 mM	0.51 mL	2.54 mL	5.08 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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