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RG-12525

RG-12525

Name: RG-12525
SKU: A19926

目录号: A19926

peptidoleukotrienes antagonist

RG-12525 Chemical Structure

CAS NO. 120128-20-3

RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 ?M.

库存：现货

规格	价格	数量
1 mg	￥ 3,024.00
5 mg	￥ 9,072.00
10 mg	￥ 15,456.00
50 mg	￥ 46,368.00

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.61 mL	118.07 mL	236.14 mL
0.5 mM	4.72 mL	23.61 mL	47.23 mL
1 mM	2.36 mL	11.81 mL	23.61 mL
5 mM	0.47 mL	2.36 mL	4.72 mL

*The above data is based on the productmolecular weight 423.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19926
M. Wt	423.47
Formula	C25H21N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	120128-20-3
Synonyms	RG12525, RG-12525, RG 12525; NID 525, NID525, NID-525
SMILES	C1(COC2=CC=C(OCC3=CC=CC=C3CC4=NN=NN4)C=C2)=NC5=CC=CC=C5C=C1