Rigosertib

目录号: A21868
multi-kinase inhibitor
Rigosertib(ON-01910)是一种多激酶抑制剂,也是一种选择性抗癌药物,它通过抑制 PI3激酶/Akt通路,促进组蛋白H2AX的磷酸化,并在细胞周期中诱导 G2/M阻滞 来诱导凋亡。
Grouped product items
规格 价格 库存 数量
2mg
¥175.00
现货
5mg
¥350.00
现货
10mg
¥630.00
现货
50mg
¥2,660.00
现货
100mg
¥5,040.00
现货
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生物活性
Discription Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle.
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A21868
分子式 C21H25NO8S
分子量 451.49
CAS号 592542-59-1
SMILES COC1=CC=C(C=C1NCC(O)=O)CS(/C=C/C2=C(C=C(C=C2OC)OC)OC)(=O)=O.[(E)]
其他名称 ON-01910, ON01910, ON 01910
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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