RK-287107

Name: RK-287107
SKU: A19113
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A19113

Tankyrase inhibitor

RK-287107 是一种强效且特异性的 tankyrase 抑制剂，其对 tankyrase-1 和 tankyrase-2 的 IC50 分别为 14.3 nM 和 10.6 nM。RK-287107 能够阻断结直肠癌细胞的生长。

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Grouped product items
规格	价格	库存
1mg	¥175.00	现货
5mg	¥455.00	现货
10mg	¥735.00	现货
25mg	¥1,435.00	现货
50mg	¥2,030.00	现货
100mg	¥2,835.00	现货
*10mM 1mL in DMSO**	¥525.00	现货
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Data Sheet

SDS

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生物活性

Discription

RK-287107 is a potent and specific tankyrase inhibitor with IC50s of 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively. RK-287107 blocks colorectal cancer cell growth.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19113
分子式	C22H26F2N4O2
分子量	416.46
CAS号	2171386-10-8
SMILES	O=C1NC(N2CCC3(CC2)CN(CCO)C4=C3C(F)=CC(F)=C4)=NC5=C1CCCC5
其他名称	RK287107, RK 287107
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	81 mg/mL (194.49 mM)
	Water	<1 mg/mL
	Ethanol	<1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.01 mL	120.06 mL	240.12 mL
0.5 mM	4.8 mL	24.01 mL	48.02 mL
1 mM	2.4 mL	12.01 mL	24.01 mL
5 mM	0.48 mL	2.4 mL	4.8 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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