RMC-4550
目录号: A18893
SHP2 inhibitor
RMC-4550 是一种强效、选择性的 SHP2 的变构抑制剂,其 IC50 为 0.583 nM。
Discription | RMC-4550 is a potent, selective and allosteric inhibitor of SHP2, with an IC50 of 0.583 nM. | |||||
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Cell Research |
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目录号 | A18893 |
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分子式 | C21H26Cl2N4O2 |
分子量 | 437.36 |
CAS号 | 2172651-73-7 |
SMILES | ClC1=C(Cl)C(C2=NC(CO)=C(N3CCC4(CO[C@@H](C)[C@H]4N)CC3)N=C2C)=CC=C1 |
其他名称 | RMC4550, RMC-4550 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 91 mg/mL (208.06 mM) | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.86 mL | 114.32 mL | 228.64 mL |
0.5 mM | 4.57 mL | 22.86 mL | 45.73 mL |
1 mM | 2.29 mL | 11.43 mL | 22.86 mL |
5 mM | 0.46 mL | 2.29 mL | 4.57 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2