RN-1734
目录号: A20616
TRPV4 antagonist
RN-1734 是 TRPV4 通道的选择性拮抗剂,完全拮抗 4αPDD 介导的 TRPV4 激活,对所有三种物种具有相当的低微摩尔 IC50 值(hTRPV4:2.3 μM,mTRPV4:5.9 μM,rTRPV4:3.2 μM)。
Discription | RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM). | |||||
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Cell Research |
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目录号 | A20616 |
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分子式 | C14H22Cl2N2O2S |
分子量 | 353.31 |
CAS号 | 946387-07-1 |
SMILES | O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O |
其他名称 | RN1734, RN 1734 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 63 mg/mL (178.31 mM) | |
Water | Insoluble | ||
Ethanol | 63 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 28.3 mL | 141.52 mL | 283.04 mL |
0.5 mM | 5.66 mL | 28.3 mL | 56.61 mL |
1 mM | 2.83 mL | 14.15 mL | 28.3 mL |
5 mM | 0.57 mL | 2.83 mL | 5.66 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2