RN-1734

目录号: A20616
TRPV4 antagonist
RN-1734 是 TRPV4 通道的选择性拮抗剂,完全拮抗 4αPDD 介导的 TRPV4 激活,对所有三种物种具有相当的低微摩尔 IC50 值(hTRPV4:2.3 μM,mTRPV4:5.9 μM,rTRPV4:3.2 μM)。
Grouped product items
规格 价格 库存 数量
5mg
¥140.00
现货
10mg
¥245.00
现货
25mg
¥525.00
现货
50mg
¥875.00
现货
100mg
¥1,400.00
现货
200mg
¥2,030.00
现货
10mM * 1mL in DMSO
¥140.00
现货
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生物活性
Discription RN-1734 is selective antagonist of the TRPV4 channel, completely antagonizes 4αPDD-mediated activation of TRPV4 with comparable, low micromolar IC50s for all three species (hTRPV4: 2.3 μM, mTRPV4: 5.9 μM, rTRPV4: 3.2 μM).
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A20616
分子式 C14H22Cl2N2O2S
分子量 353.31
CAS号 946387-07-1
SMILES O=S(C1=CC=C(Cl)C=C1Cl)(N(C(C)C)CCNC(C)C)=O
其他名称 RN1734, RN 1734
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 63 mg/mL (178.31 mM)
Water Insoluble
Ethanol 63 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.3 mL 141.52 mL 283.04 mL
0.5 mM 5.66 mL 28.3 mL 56.61 mL
1 mM 2.83 mL 14.15 mL 28.3 mL
5 mM 0.57 mL 2.83 mL 5.66 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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