RN-1747

目录号: A20615
TRPV4 agonist
RN-1747 是一种选择性的瞬时受体电位阳离子通道亚家族V成员4(TRPV4)激动剂,其半最大有效浓度(EC50)值分别为 hTRPV4 0.77 μM、mTRPV4 4.0 μM 和 rTRPV4 4.1 μM。RN-1747 还能拮抗 TRPM8,其半抑制浓度(IC50)为 4 μM。
Grouped product items
规格 价格 库存 数量
1mg
¥140.00
现货
5mg
¥245.00
现货
10mg
¥420.00
现货
25mg
¥840.00
现货
50mg
¥1,330.00
现货
100mg
¥2,275.00
现货
200mg
¥3,290.00
现货
10mM * 1mL in DMSO
¥210.00
现货
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生物活性
Discription RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM.
产品信息
目录号 A20615
分子式 C17H18ClN3O4S
分子量 395.86
CAS号 1024448-59-6
SMILES O=S(N1CCN(CC2=CC=CC=C2)CC1)(C3=CC=C(Cl)C=C3[N+]([O-])=O)=O
其他名称 RN1747; RN 1747
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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