主页 /
TGF-β / Smad /
Ro 31-8220 mesylate

Ro 31-8220 mesylate

Name: Ro 31-8220 mesylate
SKU: A13514

目录号: A13514

PKC 抑制剂

Product Citations (1)

Ro 31-8220 mesylate Chemical Structure

CAS NO. 138489-18-6

Ro 31-8220 mesylate是一种PKC抑制剂，可抑制PKC激活剂佛波肉豆蔻酸酯乙酸酯（PMA，IC50 = 1.35 x 10（-6）M）或二酰基甘油（OAG，diC8）诱导的人PMN的刺激性液体胞吞作用

库存：现货

规格	价格	数量
10 mg	￥ 840.00
25 mg	￥ 1,750.00
50 mg	￥ 2,940.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

靶点信息

PKCα	PKCβ2	PKCβ1	PKCε	PKCγ
5 nM	14 nM	24 nM	24 nM	27 nM

溶解度 *

In vitro	DMSO	85 mg/mL (153.52 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.06 mL	90.3 mL	180.6 mL
0.5 mM	3.61 mL	18.06 mL	36.12 mL
1 mM	1.81 mL	9.03 mL	18.06 mL
5 mM	0.36 mL	1.81 mL	3.61 mL

*The above data is based on the productmolecular weight 553.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A13514
作用机制	Inhibitor (抑制剂)
M. Wt	553.7
Formula	C25H23N5O2SCH3SO3H
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	138489-18-6
Synonyms	BIM IX, Bisindolylmaleimide IX (mesylate)
SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)CCCSC(=N)N.CS(=O)(=O)O