Ro 61-8048

Name: Ro 61-8048
SKU: A12833

目录号: A12833

Hydroxylase 抑制剂

Ro 61-8048 Chemical Structure

CAS NO. 199666-03-0

Ro 61-8048是有效的竞争性犬尿氨酸3-羟化酶抑制剂（Ki = 4.8 nM，IC50 = 37 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 490.00
25 mg	￥ 910.00
50 mg	￥ 1,400.00
100 mg	￥ 2,240.00

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生物活性

Ro 61-8048是有效的竞争性犬尿氨酸3-羟化酶抑制剂（Ki = 4.8 nM，IC50 = 37 nM）。

靶点信息

KMO	KMO
4.8 nM(Ki)	37 nM

溶解度 *

In vitro (25°C)	DMSO	80 mg/mL (189.82 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+30% PEG 300+5% Tween 80+ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	23.73 mL	118.64 mL	237.28 mL
0.5 mM	4.75 mL	23.73 mL	47.46 mL
1 mM	2.37 mL	11.86 mL	23.73 mL
5 mM	0.47 mL	2.37 mL	4.75 mL

*The above data is based on the productmolecular weight 421.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12833
作用机制	Inhibitor (抑制剂)
M. Wt	421.45
Formula	C17H15N3O6S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	199666-03-0
Synonyms	Ro61-8048
SMILES	COC1=C(C=C(C=C1)S(=O)(=O)NC2=NC(=CS2)C3=CC(=CC=C3)[N+](=O)[O-])OC