RO3280
目录号: A13245
PLK1 抑制剂
RO3280 是一种强效的、高度选择性的 Polo-like kinase 1 (PLK1) 抑制剂,其 IC50 为 3 nM。
Discription | RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM. | |||||
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Targets |
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Cell Research |
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目录号 | A13245 |
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分子式 | C27H35F2N7O3 |
分子量 | 543.61 |
CAS号 | 1062243-51-9 |
SMILES | CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC |
其他名称 | RO 3280, RO-3280 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 87 mg/mL (160.04 mM) | |
Water | Insoluble | ||
Ethanol | 87 mg/mL (160.04 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.4 mL | 91.98 mL | 183.96 mL |
0.5 mM | 3.68 mL | 18.4 mL | 36.79 mL |
1 mM | 1.84 mL | 9.2 mL | 18.4 mL |
5 mM | 0.37 mL | 1.84 mL | 3.68 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2