RO5126766 (CH5126766)

Name: RO5126766 (CH5126766)
SKU: A14019
Price: 315 CNY
Rating: 5 (1 reviews)

目录号: A14019

Raf/MEK dual 抑制剂

1 篇发表文献

RO5126766，也被称为CH5126766，是一种针对Raf和MEK丝裂原活化蛋白激酶（MAPKs）的特异性蛋白激酶抑制剂，具有潜在的抗肿瘤活性。

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Grouped product items
规格	价格	库存
1mg	¥315.00	现货
2mg	¥490.00	现货
5mg	¥770.00	现货
10mg	¥1,225.00	现货
25mg	¥2,380.00	现货
50mg	¥3,850.00	现货
100mg	¥5,530.00	现货
*10mM 1mL in DMSO**	¥805.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用RO5126766 (CH5126766)发表的1篇文献

Yuki Shimizu, .et al. , Cancer Lett, 2022, Sep 1;543 PMID: 35724767

生物活性

Discription

RO5126766, also known as CH5126766, is a protein kinase inhibitor specific for the Raf and MEK mitogen-activated protein kinases (MAPKs) with potential anti-neoplastic activity.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14019
分子式	C21H18FN5O5S
分子量	471.5
CAS号	946128-88-7
SMILES	CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F
其他名称	RO 5126766, RO-5126766, CH5126766, CH-5126766, CH 5126766.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	93 mg/mL (197.26 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+45% PEG 300+ddH2O	19 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.21 mL	106.04 mL	212.09 mL
0.5 mM	4.24 mL	21.21 mL	42.42 mL
1 mM	2.12 mL	10.6 mL	21.21 mL
5 mM	0.42 mL	2.12 mL	4.24 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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