微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
RO5126766 (CH5126766)是对Raf和MEK丝裂原激活的蛋白激酶（MAPK）具有特异性的蛋白激酶抑制剂，具有潜在的抗肿瘤活性。
靶点信息
| BRAF V600E | BRAF | CRAF | MEK1 | |
| 8.2 nM | 19 nM | 56 nM | 160 nM |
| In vitro (25°C) | DMSO | 93 mg/mL (197.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 5% DMSO+45% PEG 300+ddH2O | 19 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.21 mL | 106.04 mL | 212.09 mL |
| 0.5 mM | 4.24 mL | 21.21 mL | 42.42 mL |
| 1 mM | 2.12 mL | 10.6 mL | 21.21 mL |
| 5 mM | 0.42 mL | 2.12 mL | 4.24 mL |
*The above data is based on the productmolecular weight 471.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14019 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 471.5 |
| Formula | C21H18FN5O5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 946128-88-7 |
| Synonyms | RO 5126766, RO-5126766, CH5126766, CH-5126766, CH 5126766. |
| SMILES | CC1=C(C(=O)OC2=C1C=CC(=C2)OC3=NC=CC=N3)CC4=C(C(=NC=C4)NS(=O)(=O)NC)F |
产品资料
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Cobimetinib (racemate)
Cobimetinib (racemate)是一种有效的，高度选择性的MEK1/2抑制剂。
AZD6244 (Selumetinib)
Selumetinib (AZD6244)是一种有效，高选择性的MEK抑制剂，ARRY142886，AZD-6244和ARRY-142886是MEK 1/2抑制剂，GI50值在14…
Refametinib (RDEA-119, BAY 86-9766)
Refametinib (RDEA-119,BAY 86-9766)是一种口服生物利用型选择性MEK抑制剂，EC50为 2.0-15 nM。具有潜在的抗肿瘤活性…
Chlortetracycline Hydrochloride
Chlortetracycline Hydrochloride是一种特殊而有效的钙离子载体抗生素。
Keywords:购买 RO5126766 (CH5126766) | RO5126766 (CH5126766) 供应商 | 订购 RO5126766 (CH5126766) | RO5126766 (CH5126766) 价格 | RO5126766 (CH5126766) 生产商 | 订单 RO5126766 (CH5126766) | RO5126766 (CH5126766) 代理商 | 购买 946128-88-7| 946128-88-7 供应商 | 订购 946128-88-7 | 946128-88-7 价格 | 946128-88-7 生产商 | 订单 946128-88-7 | 946128-88-7 代理商|buy RO5126766 (CH5126766) | RO5126766 (CH5126766) Supplier | purchase RO5126766 (CH5126766) | RO5126766 (CH5126766) cost | RO5126766 (CH5126766) manufacturer | order RO5126766 (CH5126766) | RO5126766 (CH5126766) distributor | buy 946128-88-7| 946128-88-7 Supplier | purchase 946128-88-7 | 946128-88-7 cost | 946128-88-7 manufacturer | order 946128-88-7 | 946128-88-7 distributor