RO6889678

Name: RO6889678
SKU: A22490
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A22490

CYP3A4 inducer

RO6889678 是一种 HBV 抑制剂，具有复杂的 ADME 特性。RO6889678 在肝细胞中显示出78倍的细胞内富集，表观固有清除率为每毫克蛋白5.2微升/分钟，摄取和胆汁清除率分别为每毫克蛋白2.6和1.6微升/分钟。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥420.00	现货
5mg	¥595.00	现货
10mg	¥1,155.00	现货
25mg	¥1,925.00	现货
50mg	¥3,115.00	现货
100mg	¥4,620.00	现货
*10mM 1mL in DMSO**	¥1,120.00	现货
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Data Sheet

SDS

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生物活性

Discription

RO6889678 is an inhibitor of HBV with a complex ADME profile. RO6889678 showed an intracellular enrichment of 78-fold in hepatocytes, with an apparent intrinsic clearance of 5.2 ?l/min per mg protein and uptake and biliary clearances of 2.6 and 1.6 ?l/min per mg protein, respectively.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A22490
分子式	C21H20ClFN4O5S
分子量	494.92
CAS号	1578153-27-1
SMILES	O=C([C@H]1N(CC2=C(C(OC)=O)[C@H](C3=CC=C(F)C=C3Cl)N=C(C4=NC=CS4)N2)CCOC1)O
其他名称	RO6889678, RO-6889678, RO 6889678
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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