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ROC-325是自噬抑制剂。与现有的自噬抑制剂羟氯喹（HCQ）相比，ROC-325在具有不同遗传背景的12种不同癌细胞系中表现出优异的体外抗癌作用。
| In vitro | DMSO | 3 mg/mL (5.96 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (5.96 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.88 mL | 99.39 mL | 198.78 mL |
| 0.5 mM | 3.98 mL | 19.88 mL | 39.76 mL |
| 1 mM | 1.99 mL | 9.94 mL | 19.88 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.98 mL |
*The above data is based on the productmolecular weight 503.06. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17031 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 503.06 |
| Formula | C28H27ClN4OS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1859141-26-6 |
| Synonyms | ROC 325, ROC325 |
| SMILES | O=C1C2=C(C(C)=CC=C2NCCN(C)CCNC3=C(C=CC(Cl)=C4)C4=NC=C3)SC5=CC=CC=C51 |
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