Rodatristat ethyl

Name: Rodatristat ethyl
SKU: A20593
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A20593

TPH1 Inhibitor

Rodatristat ethyl (KAR5585) 是一种首创的口服色氨酸羟化酶1（TPH1）抑制剂，具有纳摩尔级的体外活性。Rodatristat ethyl 降低了5-羟色胺（5-HT）的水平，并显著减轻了肺动脉高压（PAH）。

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Grouped product items
规格	价格	库存
1mg	¥2,205.00	现货
5mg	¥6,125.00	现货
10mg	¥8,925.00	现货
25mg	¥16,695.00	现货
50mg	¥27,055.00	现货
100mg	¥43,575.00	现货
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Data Sheet

SDS

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生物活性

Discription	Rodatristat ethyl (KAR5585) is a first-in-class oral tryptophan hydroxylase 1 (TPH1) Inhibitor with nanomolar in vitro potency. Rodatristat ethyl reduces the level of 5-HT and significantly reduces pulmonary arterial hypertension (PAH).

产品信息

目录号	A20593
分子式	C29H31ClF3N5O3
分子量	590.04
CAS号	1673571-51-1
SMILES	ClC1=CC(C2=CC=CC=C2)=C([C@@H](OC3=NC(N)=NC(N4CCC5(CN[C@H](C(OCC)=O)C5)CC4)=C3)C(F)(F)F)C=C1
其他名称	KAR5585, KAR 5585, KAR-5585
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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