Rodatristat

Name: Rodatristat
SKU: A18820
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A18820

TPH1/TPH2 inhibitor

Rodatristat (KAR5417) 是一种强效的色氨酸羟化酶1（TPH1）和色氨酸羟化酶2（TPH2）抑制剂，其半抑制浓度（IC50s）分别为33纳摩尔和7纳摩尔，并在小鼠中显示出对肠道血清素（5-HT）水平的显著降低。

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Grouped product items
规格	价格	库存
1mg	¥2,205.00	现货
5mg	¥4,235.00	现货
10mg	¥6,825.00	现货
25mg	¥16,905.00	现货
50mg	¥22,225.00	现货
100mg	¥30,065.00	现货
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Data Sheet

SDS

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生物活性

Discription	Rodatristat (KAR5417) is a potent tryptophan hydroxylase 1 (TPH1) and TPH2 inhibitor with IC50s value of 33 nM and 7 nM, respectively, and shows robust reduction of intestinal serotonin (5-HT) levels in mice.

产品信息

目录号	A18820
分子式	C27H27ClF3N5O3
分子量	561.98
CAS号	1673568-73-4
SMILES	O=C([C@H]1NCC2(CCN(C3=NC(N)=NC(O[C@H](C4=CC=C(Cl)C=C4C5=CC=CC=C5)C(F)(F)F)=C3)CC2)C1)O
其他名称	KAR5417, KAR-5417, KAR 5417
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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