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Rolipram是一种PDE4抑制剂，IC50 = 2.0μM。
靶点信息
| PDE4 | ||||
| 2.0 μM |
| In vitro | DMSO | 48 mg/mL (174.33 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 48 mg/mL (174.33 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.32 mL | 181.62 mL | 363.24 mL |
| 0.5 mM | 7.26 mL | 36.32 mL | 72.65 mL |
| 1 mM | 3.63 mL | 18.16 mL | 36.32 mL |
| 5 mM | 0.73 mL | 3.63 mL | 7.26 mL |
*The above data is based on the productmolecular weight 275.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10805 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 275.3 |
| Formula | C16H21NO3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 61413-54-5 |
| SMILES | COC1=C(C=C(C=C1)C2CC(=O)NC2)OC3CCCC3 |
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