ROR agonist-1
目录号: A18569
ROR 激动剂
ROR agonist-1 是一种高效且可口服的 retinoic acid receptor-related orphan receptor C2 (RORC2) 的逆激动剂,能够抑制来自人类初级 TH 17 细胞的 IL-17A 产生,具有 pIC50 值为7.5。
Discription | ROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5. |
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目录号 | A18569 |
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分子式 | C21H20F6N2O5S |
分子量 | 526.45 |
CAS号 | 2361528-74-5 |
SMILES | O=C([C@H](NC(C)=O)C1=CC=C(S(=O)(CC)=O)C=C1)NC2=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C2 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2