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Roscovitine (Seliciclib)

目录号: A10806
CDK 抑制剂
Roscovitine(Seliciclib)是一种CDK抑制剂,它优先抑制包括CDK2CDK7CDK9在内的多个酶靶点。
Grouped product items
规格 价格 库存 数量
5mg
¥245.00
现货
10mg
¥315.00
现货
25mg
¥665.00
现货
50mg
¥840.00
现货
100mg
¥1,155.00
现货
200mg
¥1,610.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用Roscovitine (Seliciclib)发表的3篇文献
  • Abdel-Aziz S Shatat, .et al. , Purinergic Signal, 2024, May 27 PMID: 38801618
  • Reiko Watanabe, .et al. , J Med Chem, 2021, Mar 11;64(5):2725-2738 PMID: 33619967
  • Vimal Pandey, .et al. , Scientific Reports, 2019, 9, Article number: 5012 PMID: 30899038
  • 生物活性
    Discription Roscovitine (Seliciclib) is a CDK inhibitor that preferentially inhibit multiple enzyme targets including CDK2, CDK7 and CDK9.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A10806
    分子式 C19H26N6O
    分子量 354.5
    CAS号 186692-46-6
    SMILES CC[C@H](CO)NC1=NC2=C(C(=N1)NCC3=CC=CC=C3)N=CN2C(C)C
    其他名称 CYC202, Seliciclib
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO 69 mg/mL (194.67 mM)
    Water Insoluble
    Ethanol 6 mg/mL (16.92 mM)
    In vivo 1% DMSO+10% Tween 80+20% N-N-dimethylacetamide+69% PEG 400 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.21 mL 141.04 mL 282.09 mL
    0.5 mM 5.64 mL 28.21 mL 56.42 mL
    1 mM 2.82 mL 14.1 mL 28.21 mL
    5 mM 0.56 mL 2.82 mL 5.64 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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