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Rosuvastatin calcium (Crestor)

目录号: A10810
HMG-CoA reductase 抑制剂
罗苏瓦他汀(商名:Crestor)属于他汀类药物,用于治疗高胆固醇及相关疾病,并预防心血管疾病。罗苏瓦他汀是一种HMG-CoA还原酶的竞争性抑制剂,其作用机制与其他他汀类药物相似。
Grouped product items
规格 价格 库存 数量
5mg
¥140.00
现货
10mg
¥175.00
现货
25mg
¥210.00
现货
50mg
¥280.00
现货
100mg
¥525.00
现货
200mg
¥805.00
现货
500mg
¥1,470.00
现货
10mM * 1mL in DMSO
¥385.00
现货
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生物活性
Discription Rosuvastatin (Crestor) is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins.
产品信息
目录号 A10810
分子式 C22H28FN3O6S.1/2Ca
分子量 501.5
CAS号 147098-20-2
SMILES CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.CC(C1=NC(=NC(=C1/C=C/[C@@H](O)C[C@@H](O)CC(=O)[O-])C2=CC=C(C=C2)F)N(S(=O)(=O)C)C)C.[Ca+2]
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO Warmed: 91 mg/mL (181.79 mM)
Water Insoluble
Ethanol Insoluble
In vivo 4% DMSO+30% PEG 300+dd H2O 9 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.94 mL 99.7 mL 199.4 mL
0.5 mM 3.99 mL 19.94 mL 39.88 mL
1 mM 1.99 mL 9.97 mL 19.94 mL
5 mM 0.4 mL 1.99 mL 3.99 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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