Rottlerin

Name: Rottlerin
SKU: A20743
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A20743

PKC inhibitor

Rottlerin 是从菲律宾桑树（Mallotus Philippinensis）中提纯的天然产物，是一种特异性的 PKC 抑制剂，其对 PKCδ 的 IC50 值为 3-6 μM，对 PKCα,β,γ 的 IC50 值为 30-42 μM，对 PKCε,η,ζ 的 IC50 值为 80-100 μM。

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规格	价格	库存
5mg	¥210.00	现货
10mg	¥315.00	现货
25mg	¥700.00	现货
50mg	¥1,260.00	现货
100mg	¥2,170.00	现货
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Data Sheet

SDS

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生物活性

Discription

Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20743
分子式	C30H28O8
分子量	516.54
CAS号	CAS: 82-08-6
SMILES	O=C(C1=C2C(C=CC(C)(C)O2)=C(O)C(CC3=C(O)C(C)=C(O)C(C(C)=O)=C3O)=C1O)/C=C/C4=CC=CC=C4
其他名称	Mallotoxin; NSC 56346, NSC56346, NSC-56346; NSC 94525, NSC94525, NSC-94525
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	11 mg/mL (21.29 mM)
	Water	<1 mg/mL
	Ethanol	1 mg/mL (1.93 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.36 mL	96.8 mL	193.6 mL
0.5 mM	3.87 mL	19.36 mL	38.72 mL
1 mM	1.94 mL	9.68 mL	19.36 mL
5 mM	0.39 mL	1.94 mL	3.87 mL

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