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Rottlerin

产品详情

生物活性

Rottlerin, a natural product purified from Mallotus Philippinensis, is a specific PKC inhibitor, with IC50 values for PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM.

溶解度 *

In vitro	DMSO	11 mg/mL (21.29 mM)
	Water	<1 mg/mL
	Ethanol	1 mg/mL (1.93 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.36 mL	96.8 mL	193.6 mL
0.5 mM	3.87 mL	19.36 mL	38.72 mL
1 mM	1.94 mL	9.68 mL	19.36 mL
5 mM	0.39 mL	1.94 mL	3.87 mL

*The above data is based on the productmolecular weight 516.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A20743
M. Wt	516.54
Formula	C30H28O8
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	CAS: 82-08-6
Synonyms	Mallotoxin; NSC 56346, NSC56346, NSC-56346; NSC 94525, NSC94525, NSC-94525
SMILES	O=C(C1=C2C(C=CC(C)(C)O2)=C(O)C(CC3=C(O)C(C)=C(O)C(C(C)=O)=C3O)=C1O)/C=C/C4=CC=CC=C4