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Roy-Bz is a selecive PKCδ activator. Roy-Bz potently inhibits the proliferation of colon cancer cells by inducing a PKCδ-dependent mitochondrial apoptotic pathway involving caspase-3 activation.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.7 mL | 83.52 mL | 167.03 mL |
| 0.5 mM | 3.34 mL | 16.7 mL | 33.41 mL |
| 1 mM | 1.67 mL | 8.35 mL | 16.7 mL |
| 5 mM | 0.33 mL | 1.67 mL | 3.34 mL |
*The above data is based on the productmolecular weight 598.68. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13348 |
|---|---|
| 作用机制 | Activator (激活剂) |
| M. Wt | 598.68 |
| Formula | C36H38O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1246304-91-5 |
| SMILES | O=C1C(C(C)C)=C(OC(C2=CC=CC=C2)=O)C(C3=C1[C@H](OC(C)=O)[C@@H](OC(C4=CC=CC=C4)=O)[C@@]5([H])C(C)(C)CCC[C@]35C)=O |
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