RQ-00203078

Name: RQ-00203078
SKU: A15830
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15830

TRPM8 拮抗剂

RQ-00203078 是一种高度选择性、有效且可口服的 TRPM8 拮抗剂（IC50 值分别针对大鼠和人类通道为 5.3 和 8.3 nM），对 TRPM8 与 TRPV4、TRPV1 和 TRPA1 相比，展示出超过 350 倍的选择性。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥840.00	现货
50mg	¥1,330.00	现货
100mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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Data Sheet

SDS

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生物活性

Discription

RQ-00203078 is a highly selective, potent and orally available TRPM8 antagonist (IC50 values are 5.3 and 8.3 nM for rat and human channels respectively), exhibits >350-fold selectivity for TRPM8 over TRPV4, TRPV1 and TRPA1.

Targets

Target	Value

产品信息

目录号	A15830
分子式	C21H13ClF6N2O5S
分子量	554.85
CAS号	1254205-52-1
SMILES	ClC1=C(N(CC2=CC=C(OC(F)(F)F)C=C2)S(C3=CC=C(C(O)=O)C=C3)(=O)=O)N=CC(C(F)(F)F)=C1
其他名称	RQ 00203078, RQ00203078
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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