RS 17053 HCl
目录号: A16885
α1A antagonist
RS 17053 HCl 是一种 α1A-肾上腺素能受体拮抗剂,对 α1A 受体 具有非常高的亲和力(pKi 和 pA2 估计值为 9.1 - 9.9),并且对 α1B 和 α1D 亚型具有 30 - 100 倍的选择性(pKi 和 pA2 估计值为 7.7 - 7.8)。
Discription | RS 17053 HCl is α1A-adrenoceptor antagonist, with very high affinity for α1A receptors (pKi and pA2 estimates of 9.1 - 9.9) and a 30 - 100 fold selectivity over the α1B and α1D subtypes (pKi and pA2 estimates 7.7 - 7.8). |
---|
目录号 | A16885 |
---|---|
分子式 | C24H29N2O2Cl.HCl |
分子量 | 449.42 |
CAS号 | 169505-93-5 |
SMILES | Cl.CC(C)(CC1=CNC2=CC=C(Cl)C=C12)NCCOC1=C(OCC2CC2)C=CC=C1 |
其他名称 | RS-17053, RS17053 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2