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RU-301

RU-301

Name: RU-301
SKU: A19156

目录号: A19156

pan-TAM receptor inhibitor

RU-301 Chemical Structure

CAS NO. 1110873-99-8

RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively.

库存：现货

规格	价格	数量
1 mg	￥ 770.00
5 mg	￥ 2,240.00
10 mg	￥ 3,500.00
50 mg	￥ 10,500.00

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生物活性

溶解度 *

In vitro	DMSO	84 mg/mL (174.83 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (4.16 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.81 mL	104.07 mL	208.13 mL
0.5 mM	4.16 mL	20.81 mL	41.63 mL
1 mM	2.08 mL	10.41 mL	20.81 mL
5 mM	0.42 mL	2.08 mL	4.16 mL

*The above data is based on the productmolecular weight 480.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19156
作用机制	Inhibitor (抑制剂)
M. Wt	480.46
Formula	C21H19F3N4O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	1110873-99-8
Synonyms	RU 301; RU301
SMILES	O=C(NCCNC1=CC=C(C(F)(F)F)C=C1[N+]([O-])=O)C2=CC=CC=C2SCC3=CC(C)=NO3