RU-301
目录号: A19156
pan-TAM receptor inhibitor
RU-301 是一种 pan-TAM 受体抑制剂,通过在 Gas6 和相应 TAMs 的 Ig1 领域之间的接口处结合,展现 pan-TAM 抑制活性,其 Kd 和 IC50 值分别为 12 微摩尔和 10 微摩尔。
Discription | RU-301 is a pan-TAM receptor inhibitor, exerts pan-TAM inhibitory activity by binding at the interface between Gas6 and the Ig1 domain of the respective TAMs with Kd and IC50 values of 12 μM and 10 μM, respectively. |
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目录号 | A19156 |
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分子式 | C21H19F3N4O4S |
分子量 | 480.46 |
CAS号 | 1110873-99-8 |
SMILES | O=C(NCCNC1=CC=C(C(F)(F)F)C=C1[N+]([O-])=O)C2=CC=CC=C2SCC3=CC(C)=NO3 |
其他名称 | RU 301; RU301 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 84 mg/mL (174.83 mM) | |
Water | Insoluble | ||
Ethanol | 2 mg/mL (4.16 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 20.81 mL | 104.07 mL | 208.13 mL |
0.5 mM | 4.16 mL | 20.81 mL | 41.63 mL |
1 mM | 2.08 mL | 10.41 mL | 20.81 mL |
5 mM | 0.42 mL | 2.08 mL | 4.16 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2