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Ruboxistaurin (LY333531)是一种有效的蛋白激酶C同工酶，PKCβI（IC50 = 4.7 nM）和PKCβII（IC50 = 5.9 nM）的选择性抑制剂。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.34 mL | 106.71 mL | 213.42 mL |
| 0.5 mM | 4.27 mL | 21.34 mL | 42.68 mL |
| 1 mM | 2.13 mL | 10.67 mL | 21.34 mL |
| 5 mM | 0.43 mL | 2.13 mL | 4.27 mL |
*The above data is based on the productmolecular weight 468.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12399 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 468.55 |
| Formula | C28H28N4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 169939-94-0 |
| Synonyms | LY 333531, LY 333531 |
| SMILES | CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O |
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