Apabetalone (RVX-208)

Name: Apabetalone (RVX-208)
SKU: A13956
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A13956

BET bromodomain 抑制剂

RVX-208 是一种强效的 BET 溴结构域抑制剂，其对 BD2 的 IC50 为 0.510 uM，对 BD1 的选择性约为 170 倍。

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Grouped product items
规格	价格	库存
10mg	¥210.00	现货
25mg	¥455.00	现货
50mg	¥770.00	现货
100mg	¥1,155.00	现货
500mg	¥2,940.00	现货
*10mM 1mL in DMSO**	¥245.00	现货
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Data Sheet

SDS

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生物活性

Discription

RVX-208 is a potent BET bromodomain inhibitor with IC50 of 0.510 uM for BD2, about 170-fold selectivity over BD1.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A13956
分子式	C20H22N2O5
分子量	370.4
CAS号	1044870-39-4
SMILES	CC1=CC(=CC(=C1OCCO)C)C2=NC(=O)C3=C(C=C(C=C3N2)OC)OC
其他名称	RVX-000222
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	63 mg/mL (170.08 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC Na (1N HCl, PH 2.5-3.0)	7 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27 mL	134.99 mL	269.98 mL
0.5 mM	5.4 mL	27 mL	54 mL
1 mM	2.7 mL	13.5 mL	27 mL
5 mM	0.54 mL	2.7 mL	5.4 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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