(S)-10-Hydroxycamptothecin

Name: (S)-10-Hydroxycamptothecin
SKU: A11997
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A11997

Topoisomerase

(S)-10-羟基喜树碱是一种喜树碱衍生物，它通过在染色体DNA中引起链断裂并诱导凋亡来抑制DNA拓扑异构酶。

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Grouped product items
规格	价格	库存
25mg	¥245.00	现货
50mg	¥385.00	现货
100mg	¥525.00	现货
250mg	¥980.00	现货
500mg	¥1,330.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11997
分子式	C20H16N2O5
分子量	364.35
CAS号	19685-09-7
SMILES	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O
其他名称	HCPT;SN38;Ampule;NSC 107124;HYDROCAMPTOTHECINE;HYDROXYCAMPTOTHECIN;
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 7 mg/mL (19.21 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.45 mL	137.23 mL	274.46 mL
0.5 mM	5.49 mL	27.45 mL	54.89 mL
1 mM	2.74 mL	13.72 mL	27.45 mL
5 mM	0.55 mL	2.74 mL	5.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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