(S)-crizotinib

Name: (S)-crizotinib
SKU: A14291
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A14291

MTH1 (NUDT1) 抑制剂

(S)-crizotinib，crizotinib的(S)-对映体，是一种强效的 MTH1 (NUDT1) 抑制剂，其 IC50 为72 nM。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥630.00	现货
25mg	¥1,050.00	现货
50mg	¥1,575.00	现货
100mg	¥2,520.00	现货
*10mM 1mL in DMSO**	¥455.00	现货
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Data Sheet

SDS

Other Forms of (S)-crizotinib

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生物活性

Discription

(S)-crizotinib, the (S)-enantiomer of crizotinib, is a potent MTH1 (NUDT1) inhibitor with IC50 of 72 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A14291
分子式	C21H22Cl2FN5O
分子量	450.34
CAS号	1374356-45-2
SMILES	C[C@@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 42 mg/mL (93.26 mM)
	Water	Insoluble
	Ethanol	22 mg/mL (48.85 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.21 mL	111.03 mL	222.05 mL
0.5 mM	4.44 mL	22.21 mL	44.41 mL
1 mM	2.22 mL	11.1 mL	22.21 mL
5 mM	0.44 mL	2.22 mL	4.44 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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