(S)-ML753286

Name: (S)-ML753286
SKU: A20588
Price: 3430 CNY
Rating: 5 (288 reviews)

目录号: A20588

BCRP inhibitor

(S)-ML753286 是一种乳腺癌耐药蛋白（BCRP）抑制剂，其对 BCRP 外排转运蛋白的 IC50 为 0.6 μM。

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规格	价格	库存
5mg	¥3,430.00	现货
10mg	¥5,915.00	现货
25mg	¥10,605.00	现货
50mg	¥13,825.00	现货
100mg	¥17,465.00	现货
*10mM 1mL in DMSO**	¥3,535.00	现货
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Data Sheet

SDS

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生物活性

Discription

(S)-ML753286 is a breast cancer resistance protein (BCRP) inhibitor with an IC50 of 0.6 μM on BCRP efflux transporter.

Cell Research

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Cell Line	Type	Value	Description	References
Caco-2	IC50	> 30 μM	Inhibition of P-gp transporter in human Caco2 cells using [3H]-digoxin as substrate measured at 30 to 120 mins by microplate scintillation and luminescence counting analysis	[PMID: 26642765]
Caco-2	IC50	0.6 μM	Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate measured at 30 to 120 mins by microplate scintillation and luminescence counting analysis	[PMID: 26642765]
Caco-2	IC50	0.61 μM	Inhibition of BCRP in human Caco2 cells using 3H-Estron-3-sulfate as substrate assessed as Ko143 IC50 measured at 30 to 120 mins by microplate scintillation and luminescence counting analysis	[PMID: 26642765]

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产品信息

目录号	A20588
分子式	C20H25N3O3
分子量	355.43
CAS号	1699720-85-8
SMILES	COC1=CC=C2C(NC3=C2C[C@]4([H])N(C([C@H](C)NC4=O)=O)[C@H]3CC(C)C)=C1
其他名称	ML 753286, ML-753286
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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