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S(-)-Propranolol HCl是一种非选择性的β-肾上腺素能受体（βAR）拮抗剂，对β1AR和β2AR具有高亲和力，Ki值分别为1.8 nM和0.8 nM。 盐酸普萘洛尔抑制[3H] -DHA与大鼠脑膜制剂的结合，IC50为12 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 33.81 mL | 169.03 mL | 338.07 mL |
| 0.5 mM | 6.76 mL | 33.81 mL | 67.61 mL |
| 1 mM | 3.38 mL | 16.9 mL | 33.81 mL |
| 5 mM | 0.68 mL | 3.38 mL | 6.76 mL |
*The above data is based on the productmolecular weight 295.8. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13428 |
|---|---|
| 作用机制 | Blocker (阻断剂) |
| M. Wt | 295.8 |
| Formula | C16H22ClNO2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | CAS: 4199-10-4 |
| Synonyms | S-(-)-PROPANOLOL HCL, (S)-PROPRANOLOL HYDROCHLORIDE |
| SMILES | CC(C)NC[C@@H](COC1=CC=CC2=CC=CC=C21)O.Cl |
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