(S,R,S)-AHPC TFA

Name: (S,R,S)-AHPC TFA
SKU: A19593
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A19593

(S,R,S)-AHPC TFA (MDK7526 TFA) 是基于 VH032 的 VHL 配体，用于招募 von Hippel-Lindau (VHL) 蛋白。(S,R,S)-AHPC TFA (MDK7526 TFA) 可以通过连接器与蛋白配体（例如，BCR-ABL1）连接，形成 PROTACs（例如，GMB-475）。GMB-475 在 Ba/F3 细胞中诱导 BCR-ABL1 的降解，具有 IC50 为 1.11 μM。

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规格	价格	库存
5mg	¥175.00	现货
10mg	¥280.00	现货
25mg	¥455.00	现货
50mg	¥665.00	现货
100mg	¥1,085.00	现货
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Data Sheet

SDS

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生物活性

Discription

(S,R,S)-AHPC TFA (MDK7526 TFA) is the VH032-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL) protein. (S,R,S)-AHPC TFA (MDK7526 TFA) can be connected to the ligand for protein (e.g., BCR-ABL1) by a linker to form PROTACs (e.g., GMB-475). GMB-475 induces the degradation of BCR-ABL1 with an IC50 of 1.11 μM in Ba/F3 cells.

Targets

Target	Value

产品信息

目录号	A19593
分子式	C24H31F3N4O5S
分子量	544.59
CAS号	1631137-51-3
SMILES	FC(F)(F)C(O)=O.O=C([C@H](C[C@@H](O)C1)N1C([C@@H](N)C(C)(C)C)=O)NCC2=CC=C(C(SC=N3)=C3C)C=C2
其他名称	MDK7526 TFA, MDK 7526, MDK-7526; VH032-NH2 TFA; VHL ligand 1 TFA
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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