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(S)-(+)-Rolipram

目录号: A10816
PDE4 抑制剂
(S)-(+)-罗利普兰 ((+)-罗利普兰) 是一种特异性针对环磷酸腺苷(cAMP)的磷酸二酯酶4(PDE4)抑制剂,其半抑制浓度(IC50)为1100纳摩尔。 (S)-(+)-罗利普兰能够抑制人类单核细胞产生肿瘤坏死因子-α(TNFα)。
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规格 价格 库存 数量
2mg
¥175.00
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5mg
¥245.00
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10mg
¥455.00
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25mg
¥910.00
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50mg
¥1,505.00
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100mg
¥2,275.00
现货
10mM * 1mL in DMSO
¥280.00
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生物活性
Discription (S)-(+)-Rolipram ((+)-Rolipram) is a cyclic AMP(cAMP)-specific phosphodiesterase 4 (PDE4) inhibitor, with an IC50 of 1100 nM. (S)-(+)-Rolipram can suppresse tumor necrosis factor-alpha (TNFα) production by human mononuclear cells.
产品信息
目录号 A10816
分子式 C16H21NO3
分子量 275.34
CAS号 85416-73-5
SMILES O=C1NC[C@H](C2=CC=C(OC)C(OC3CCCC3)=C2)C1
其他名称 (+)-Rolipram; (S)-Rolipram
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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