微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
S-Ruxolitinib是INCB018424的手性化合物，是一种有效且选择性的小分子Janus激酶1（JAK1）和JAK2抑制剂。
Targets
| Target | Value |
|---|---|
| JAK2 | IC50: 2.8nM |
| JAK1 | IC50: 3.3nM |
| TYK2 | IC50: 19nM |
| JAK3 | IC50: 428nM |
| Chk2 | IC50: >1μM |
| c-Met | IC50: >10μM |
| In vitro (25°C) | DMSO | 59 mg/mL (192.57 mM) | |
| Water | 5 mg/mL (16.32 mM) | ||
| Ethanol | 59 mg/mL (192.57 mM) | ||
| In vivo | 0.5% CMC+0.25% Tween 80 | 28 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 32.64 mL | 163.2 mL | 326.4 mL |
| 0.5 mM | 6.53 mL | 32.64 mL | 65.28 mL |
| 1 mM | 3.26 mL | 16.32 mL | 32.64 mL |
| 5 mM | 0.65 mL | 3.26 mL | 6.53 mL |
*The above data is based on the productmolecular weight 306.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A14955 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 306.37 |
| Formula | C17H18N6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 941685-37-6 |
| Synonyms | INCB018424 |
| SMILES | C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 S-Ruxolitinib | S-Ruxolitinib 供应商 | 订购 S-Ruxolitinib | S-Ruxolitinib 价格 | S-Ruxolitinib 生产商 | 订单 S-Ruxolitinib | S-Ruxolitinib 代理商 | 购买 941685-37-6| 941685-37-6 供应商 | 订购 941685-37-6 | 941685-37-6 价格 | 941685-37-6 生产商 | 订单 941685-37-6 | 941685-37-6 代理商|buy S-Ruxolitinib | S-Ruxolitinib Supplier | purchase S-Ruxolitinib | S-Ruxolitinib cost | S-Ruxolitinib manufacturer | order S-Ruxolitinib | S-Ruxolitinib distributor | buy 941685-37-6| 941685-37-6 Supplier | purchase 941685-37-6 | 941685-37-6 cost | 941685-37-6 manufacturer | order 941685-37-6 | 941685-37-6 distributor