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S-Ruxolitinib

目录号: A14955
JAK 抑制剂
S-Ruxolitinib 是 INCB018424 的手性形式,是一种强效且选择性的小分子 Janus kinase 1 (JAK1)JAK2 抑制剂。
Grouped product items
规格 价格 库存 数量
5mg
¥350.00
现货
10mg
¥420.00
现货
50mg
¥770.00
现货
100mg
¥1,050.00
现货
10mM * 1mL in DMSO
¥350.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription S-Ruxolitinib is the chirality of INCB018424, is a potent and selective small-molecule Janus kinase 1 (JAK1) and JAK2 inhibitor.
Targets
Target Value
产品信息
目录号 A14955
分子式 C17H18N6
分子量 306.37
CAS号 941685-37-6
SMILES C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3
其他名称 INCB018424
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO 59 mg/mL (192.57 mM)
Water 5 mg/mL (16.32 mM)
Ethanol 59 mg/mL (192.57 mM)
In vivo 0.5% CMC+0.25% Tween 80 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.64 mL 163.2 mL 326.4 mL
0.5 mM 6.53 mL 32.64 mL 65.28 mL
1 mM 3.26 mL 16.32 mL 32.64 mL
5 mM 0.65 mL 3.26 mL 6.53 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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