S-Ruxolitinib
目录号: A14955
JAK 抑制剂
S-Ruxolitinib 是 INCB018424 的手性形式,是一种强效且选择性的小分子 Janus kinase 1 (JAK1) 和 JAK2 抑制剂。
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重要通知:仅供研究使用。我们不向患者销售。
重要通知:仅供研究使用。我们不向患者销售。
Discription | S-Ruxolitinib is the chirality of INCB018424, is a potent and selective small-molecule Janus kinase 1 (JAK1) and JAK2 inhibitor. | ||
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Targets |
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目录号 | A14955 |
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分子式 | C17H18N6 |
分子量 | 306.37 |
CAS号 | 941685-37-6 |
SMILES | C1CCC(C1)C(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC=N3 |
其他名称 | INCB018424 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 59 mg/mL (192.57 mM) | |
Water | 5 mg/mL (16.32 mM) | ||
Ethanol | 59 mg/mL (192.57 mM) | ||
In vivo | 0.5% CMC+0.25% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 32.64 mL | 163.2 mL | 326.4 mL |
0.5 mM | 6.53 mL | 32.64 mL | 65.28 mL |
1 mM | 3.26 mL | 16.32 mL | 32.64 mL |
5 mM | 0.65 mL | 3.26 mL | 6.53 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2