S18-000003

Name: S18-000003
SKU: A19105

目录号: A19105

RORγt 抑制剂

S18-000003 Chemical Structure

CAS NO. 2068119-11-7

S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production.

库存：现货

规格	价格	数量
5 mg	￥ 2,450.00
10 mg	￥ 4,550.00
50 mg	￥ 14,000.00

大包装询价

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

S18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.28 mL	96.42 mL	192.85 mL
0.5 mM	3.86 mL	19.28 mL	38.57 mL
1 mM	1.93 mL	9.64 mL	19.28 mL
5 mM	0.39 mL	1.93 mL	3.86 mL

*The above data is based on the productmolecular weight 518.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19105
作用机制	Inhibitor (抑制剂)
M. Wt	518.55
Formula	C26H25F3N2O4S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	2068119-11-7
Synonyms	S18000003, S18 000003
SMILES	FC1=C(NC(C(C)(C)C2=CC=C(NC(CC3=CC=C(S(CC)(=O)=O)C=C3)=O)C=C2F)=O)C=CC(F)=C1