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S1RA是一种选择性sigma-1受体拮抗剂，据报道其结合亲和力为Ki = 17.0±7.0 nM，对sigma-2受体具有选择性，并且对其他170种受体，酶，转运蛋白和离子通道具有选择性。
| In vitro | DMSO | 63 mg/mL (186.71 mM) | |
| Water | 63 mg/mL (186.71 mM) | ||
| Ethanol | 18 mg/mL (53.34 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.64 mL | 148.18 mL | 296.37 mL |
| 0.5 mM | 5.93 mL | 29.64 mL | 59.27 mL |
| 1 mM | 2.96 mL | 14.82 mL | 29.64 mL |
| 5 mM | 0.59 mL | 2.96 mL | 5.93 mL |
*The above data is based on the productmolecular weight 337.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A12504 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 337.42 |
| Formula | C20H23N3O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 878141-96-9 |
| Synonyms | E52862, E 52862, MR390; MR 390; MR-390 |
| SMILES | CC1=CC(=NN1C2=CC3=CC=CC=C3C=C2)OCCN4CCOCC4 |
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