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S29434 (NMDPEF) is a potent, competitive, selective and cell-permeable inhibitor of quinone reductase 2 (QR2), with IC50s ranging from 5 to 16 nM for human QR2 at different organizational levels, and has good selectivity for QR2 over QR1.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.71 mL | 133.55 mL | 267.1 mL |
| 0.5 mM | 5.34 mL | 26.71 mL | 53.42 mL |
| 1 mM | 2.67 mL | 13.36 mL | 26.71 mL |
| 5 mM | 0.53 mL | 2.67 mL | 5.34 mL |
*The above data is based on the productmolecular weight 374.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22217 |
|---|---|
| M. Wt | 374.39 |
| Formula | C21H18N4O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 874484-20-5 |
| Synonyms | NMDPEF |
| SMILES | O=C(C1=CC=CO1)NCCC2=C(C3=NC=CC=C3C4)N4C5=CC=C(OC)N=C52 |
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