Sabutoclax

Name: Sabutoclax
SKU: A12823
Price: 385 CNY
Rating: 5 (1 reviews)

目录号: A12823

Bcl-2 抑制剂

1 篇发表文献

Sabutoclax（BI-97C1）是一种泛Bcl-2抑制剂，包括对Bcl-xL、Bcl-2、Mcl-1和Bfl-1的抑制，其IC50分别为0.31 μM、0.32 μM、0.20 μM和0.62 μM。

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Grouped product items
规格	价格	库存
1mg	¥385.00	现货
5mg	¥980.00	现货
10mg	¥1,680.00	现货
25mg	¥2,205.00	现货
50mg	¥4,060.00	现货
100mg	¥7,455.00	现货
*10mM 1mL in DMSO**	¥1,120.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Sabutoclax发表的1篇文献

Christopher D. Graham, .et al. , Oncotarget, 2017, Jan 31; 8(5): 8670-8678 PMID: 28055968

生物活性

Discription

Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A12823
分子式	C42H40N2O8
分子量	700.78
CAS号	1228108-65-3
SMILES	CC1=C(C(=C2C=C(C(=C(C2=C1)C(=O)NC[C@H](C)C3=CC=CC=C3)O)O)O)C4=C(C=C5C(=C4O)C=C(C(=C5C(=O)NC[C@H](C)C6=CC=CC=C6)O)O)C
其他名称	BI-97C1,BI97C1
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 93 mg/mL (132.7 mM)
	Water	Insoluble
	Ethanol	Warmed: 50 mg/mL (71.34 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.27 mL	71.35 mL	142.7 mL
0.5 mM	2.85 mL	14.27 mL	28.54 mL
1 mM	1.43 mL	7.13 mL	14.27 mL
5 mM	0.29 mL	1.43 mL	2.85 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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